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KMID : 0359720130310040262
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Journal of the Korean Neurological Association
2013 Volume.31 No. 4 p.262 ~ p.265
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Primary Angiitis of the Central Nervous System Diagnosed by High-Resolution Vessel Wall MRI
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Cho Eun-Bin
Kim Suk-Jae
Cha Ji-Hoon
Son Tae-Ok
Kim Jun-Pyo
Bang Oh-Young
Kim Gyeong-Moon
Chung Chin-Sang
Lee Kwang-Ho
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Abstract
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Primary angiitis of the central nervous system (PACNS) is a poorly understood form of vascular inflammatory disease that is restricted to the brain and spinal cord. A 38-year-old woman presented with severe headache and transient aphasia. Her cerebrospinal fluid exhibited aseptic meningitis, and high-resolution vessel-wall MRI (HRVW-MRI) revealed narrowing of multiple intracranial vessels with concentric wall thickening and diffuse enhancement, suggestive of PACNS. High-dose steroid and azathioprine therapy resulted in a significant improvement in vessel wall thickening, and enhancement was observed on the follow-up HRVW-MRI
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KEYWORD
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PACNS, Vessel-wall MRI, Therapeutic monitoring
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